Product description

HCU Lophlex Neutral is a Food for Special Medical Purposes for use under medical supervision. A methionine-free amino acid-based powder, containing a balanced mix of essential and non-essential amino acids, vitamins, trace elements and some minerals. Contains docosahexaenoic acid (DHA) as the intake of this essential fatty acid may be low in protein restricted diets. With sugar and sweetener.
Pack size: 29g sachet (containing 20g protein equivalent)

Must be used under medical supervision. Not suitable as a sole source of nutrition. Not suitable for children under 3 years of age. Not suitable for tube feeding. Only intended for use by individuals with proven homocystinuria (HCU)/CBS deficiency or hypermethioninemia.

This product must be supplemented with natural protein, fluid and other nutrients in medically prescribed quantities to supply the methionine and general nutrition requirements of the patient. Please monitor micronutrient intake to ensure that individual’s intakes are optimal. The product contains only trace amounts of sodium, potassium and chloride.

The recommended dosage and timing of intake is dependent on the age, bodyweight and medical condition of the patient, and should be determined by a dietitian or clinician only. The required daily amount should be divided into equal portions and distributed throughout the day. Water or diluted drinks should be offered or taken at the same time. To ensure tolerance the product may initially need to be introduced at a lower concentration. The quantity and dilution of this product can be adapted to the tolerance and preferences of the individual under supervision of a clinician or dietitian.

Recommended feed dilution:
29g of product made up to a final volume of approximately 80ml.

  • 1 sachet = 29g powder
  • 1 sachet + 65ml water = approximately 80ml
  • One sachet (29g) provides 20g protein equivalent

Best prepared with chilled water and consumed immediately after preparation.
Do not boil and do not use a microwave oven to heat.
Do not freeze.

Store in a cool, dry place.
Once sachet is opened, use immediately.
Once reconstituted, keep refrigerated and use within 24 hours. Shake or stir immediately before use.

Halal

L-leucine, L-lysine acetate, L-proline, dried glucose syrup, L-aspartic acid, L-tyrosine, L- glutamine, glycine, L-arginine, L-valine, L-serine, L-isoleucine, calcium hydrogen phosphate, L-alanine, L-threonine, L-phenylalanine, L-cystine, L-histidine, magnesium acetate, flavouring, choline bitartrate, L-tryptophan, oil from Crypthecodinium cohnii, stabiliser (E412), modified starch (E1450), potassium citrate, flavour enhancer (E330), calcium phosphate, taurine, sodium L-ascorbate, high oleic sunflower oil, inositol, potassium phosphate monobasic, ferrous sulphate, L-carnitine, zinc sulphate, nicotinamide, DL-ɑ-tocopheryl acetate, artificial sweetener (sucralose), calcium Dpantothenate, copper sulphate, manganese sulphate, pyridoxine hydrochloride, thiamin hydrochloride, riboflavin, retinyl acetate, folic acid, potassium iodide, sodium molybdate, D-biotin, sodium selenite, chromium chloride, phytomenadione, cholecalciferol, cyanocobalamin.

Allergy Advice: For allergens, see ingredients in bold.

Nutritional information per100 g29 g
ENERGY1436 kJ / 338 kcal416 kJ / 98 kcal
FAT of which1.4 g0.42 g
-Saturates0.50 g0.15 g
-Monounsaturates0.34 g0.10 g
-Polyunsaturates0.57 g0.16 g
-Docosahexaenoic acid (DHA)0.52 g150 mg
CARBOHYDRATE of which13.4 g3.9 g
Sugars1.0 g0.30 g
FIBRE0.79 g0.23 g
PROTEIN EQUIVALENT of which68.9 g20.0 g
L-Alanine3.72 g1.08 g
L-Arginine4.69 g1.36 g
L-Aspartic acid5.38 g1.56 g
L-Cystine3.10 g0.90 g
L-Glutamic acid--
L-Glutamine5.10 g1.48 g
Glycine5.03 g1.46 g
L-Histidine2.69 g0.78 g
L-Isoleucine4.28 g1.24 g
L-Leucine7.24 g2.10 g
L-Lysine4.901.42
L-Methionine--
L-Phenylalanine3.17 g0.92 mg
L-Proline6.34 g1.84 g
L-Serine4.34 g1.26 g
L-Threonine3.52 g1.02 g
L-Tryptophan1.45 g0.42 g
L-Tyrosine5.24 g1.52 g
L-Valine4.62 g1.34 g
SALT<0.15 g<0.04 g
VITAMINS
Vitamin A982 µg285 µg
Vitamin D27.6 µg8.0 µg
Vitamin E11.0 mg (α-TE/ET)3.20 mg (α-TE/ET)
Vitamin C126 mg36.6 mg
Vitamin K86.0 µg24.9 µg
Thiamin1.46 mg0.42 mg
Riboflavin1.72 mg0.50 mg
Niacin24.5 mg7.10 mg
Niacin46.9 mg NE/EN13.6 mg NE/EN
Vitamin B62.0 mg0.58 mg
Folic acid345 µg100 µg
Vitamin B126.20 µg1.80 µg
Biotin184 µg53.4 µg
Pantothenic acid6.90 mg2.0 mg
MINERALS & TRACE ELEMENTS
Sodium<60.0 mg<17.4 mg
Potassium345 mg100 mg
Chlorine<50.0 mg<14.5 mg
Calcium1276 mg370 mg
Phosphorous966 mg280 mg
Magnesium369 mg107 mg
Iron18.3 mg5.30 mg
Zinc13.4 mg3.90 mg
Copper1.84 mg0.53 mg
Manganese1.84 mg0.53 mg
Iodine202 µg58.4 µg
Molybdenum86.2 µg25.0 µg
Selenium92.2 µg26.8 µg
Chromium36.5 µg10.6 µg
OTHERS
L-Carnitine31.0 mg9.0 mg
Choline526 mg153 mg
Inositol140 mg40.6 mg
Taurine233 mg67.6 mg
Osmolality 2016 mOsmol/kg H₂O
Osmolarity 1552 mOsmol/l


-Each sachet contains 29g of powder
*Nil added
**At the recommended feed concentration (e.g. 29g powder + 65ml water = approx. 80ml)
03-2020

Disclaimer

HCU Lophlex Neutral is a Food for Special Medical Purposes for the dietary management of proven homocystinuria (HCU) in children aged 3 years and onwards and adults, including pregnant women (in conjunction with standard folic acid supplementation), and must be used under medical supervision. Always follow the advice of your treating dietitian before making any changes to the diet. Consult with your treating dietitian whether HCU Lophlex neutral is suitable for you or your child.

*DHA - docosahexaenoic acid (an omega-3 fatty acid to address your specific dietary requirements)

**HCU Lophlex Powder is the lowest volume powdered protein substitute available for use in the UK & Irish market for people with HCU from 3 years of age and adults. Only 65mls of water per sachet is required to make a low volume drink containing 20g PE. Accurate in MIMS UK & IRE (November 2025)

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