{"id":1250,"date":"2019-03-27T22:02:29","date_gmt":"2019-03-28T02:02:29","guid":{"rendered":"https:\/\/nutriciametabolics.expressodesign.com\/?p=1250"},"modified":"2025-05-16T06:56:55","modified_gmt":"2025-05-16T10:56:55","slug":"blog-what-is-gmp","status":"publish","type":"post","link":"https:\/\/www.nutriciametabolics.com\/en-us\/blog\/what-is-gmp\/","title":{"rendered":"What is GMP?"},"content":{"rendered":"\n<figure class=\"wp-block-image alignwide size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"530\" src=\"https:\/\/www.nutriciametabolics.com\/wp-content\/uploads\/2021\/08\/CheeseMaker.jpg\" alt=\"\" class=\"wp-image-7115\" srcset=\"https:\/\/www.nutriciametabolics.com\/en-us\/wp-content\/uploads\/2021\/08\/CheeseMaker.jpg 800w, https:\/\/www.nutriciametabolics.com\/en-us\/wp-content\/uploads\/2021\/08\/CheeseMaker-300x199.jpg 300w, https:\/\/www.nutriciametabolics.com\/en-us\/wp-content\/uploads\/2021\/08\/CheeseMaker-768x509.jpg 768w, https:\/\/www.nutriciametabolics.com\/en-us\/wp-content\/uploads\/2021\/08\/CheeseMaker-400x265.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image alignleft size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"189\" src=\"https:\/\/www.nutriciametabolics.com\/wp-content\/uploads\/2019\/03\/What-Is-GMP-sm.jpg\" alt=\"What is GMP icon\" class=\"wp-image-6019\"\/><\/figure>\n\n\n\n<p>You\u2019ve likely seen \u2018GMP\u2019 on a <a href=\"\/en-us\/pku\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Phenylketonuria (PKU)<\/strong><\/a> or <a href=\"\/en-us\/tyr\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Tyrosinemia (TYR)<\/strong><\/a> formula label or heard about it through your dietitian. But what exactly is it and why is it getting so popular? GMP can be used as a protein source for PKU and Tyrosinemia formulas. GMP, short for&nbsp;glycomacropeptide, is a peptide \u2013 a type of short protein. Peptides typically consist of shorter chains of amino acids, whereas true proteins are larger and more complex structures. You might find it interesting that GMP is a byproduct of the cheesemaking process.<\/p>\n\n\n\n<p>Contrary to other proteins, pure GMP does not contain phenylalanine (PHE), tyrosine (TYR) and a couple of other amino acids. That\u2019s why it is a suitable protein source for PKU and Tyrosinemia formulas. However, through the process of isolating GMP from the whey part of the milk, some very small amounts of PHE and TYR cannot be filtered from the actual GMP and are part of the GMP ingredient used in PKU and Tyrosinemia formulas.<\/p>\n\n\n\n<p>GMP by itself lacks certain amino acids that are important for growth and development. These amino acids must be added to the formulas so that PKU and TYR formulas are appropriate for individuals with PKU or Tyrosinemia. That\u2019s why you see GMP and free amino acids listed as ingredients on your PKU and Tyrosinemia formula label.<\/p>\n\n\n\n<p>You may have noticed slight variations in the PHE content when comparing GMP formulas (for example, between 10\u201018 mg PHE per 10 g protein equivalent). Healthcare professionals have told us, that the differences are so small that they are clinically not relevant, and studies support this. This means that if a GMP\u2010based product is appropriate for someone with PKU or Tyrosinemia, the slight differences in PHE content are not important.<\/p>\n\n\n\n<p>GMP is still a growing concept, but several studies support that GMP\u2010based products are safe and appropriate for most individuals with PKU or Tyrosinemia. GMP\u2010based products have a milder taste, and that milder taste is often preferred over amino acid\u2010based products. Finding a formula you or your child like is very important as that can certainly help with diet adherence. In addition, a small number of studies also report that patients feel fuller when consuming a GMP\u2010based formula.<\/p>\n\n\n\n<p>A small number of clinical studies are also looking into other benefits of GMP\u2010based products in metabolics. However, the results of these studies are inconclusive. More research is needed to provide definite answers.<\/p>\n\n\n\n<p>For some people with PKU or Tyrosinemia, the amount of PHE in GMP\u2010based formulas may be too high. Rest assured that formulas that are based 100% on amino acids (with no GMP) provide you or your child with all the nutrients needed for proper growth and development, including important vitamins and minerals for bone health. But of course, your dietitian can advise you on which formula is best for you or your child.<\/p>\n\n\n\n<p>Want to find a GMP-based formula? You\u2019ve come to the right place! Click on a product below to find out more information.<\/p>\n\n\n\n<figure class=\"wp-block-image alignleft size-large\"><a href=\"\/en-us\/blog\/nutricias-gmp-based-formulas\/\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.nutriciametabolics.com\/wp-content\/uploads\/2021\/01\/nutriciametabolics-blog-gmp-based-formulas-1024x270.jpg\" alt=\"GMP-based formulas\" class=\"wp-image-2076\"\/><\/a><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>Always talk to your dietitian before making any diet changes \u2013 and contact us if you have any questions about metabolic formulas.<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-css-opacity is-style-wide\"\/>\n\n\n\n<p class=\"has-small-font-size\">PhenylAde GMP ULTRA, PhenylAde GMP READY, PhenylAde GMP Drink Mix, and PhenylAde GMP Mix-In are medical foods for the dietary management of proven Phenylketonuria (PKU) and must be used under medical supervision.&nbsp; TYR Lophlex GMP Mix-In is a medical food for the dietary management of proven Tyrosinemia and must be used under medical supervision.<\/p>\n\n\n\n<p class=\"has-small-font-size\">\u00a9 2020 Nutricia North America<\/p>\n","protected":false},"excerpt":{"rendered":"<p>You\u2019ve likely seen \u2018GMP\u2019 on a Phenylketonuria (PKU) or Tyrosinemia (TYR) formula label or heard about it through your dietitian. But what exactly is it and why is it getting so popular? GMP can be used as a protein source for PKU and Tyrosinemia formulas. GMP, short for&nbsp;glycomacropeptide, is a peptide \u2013 a type of [&hellip;]<\/p>\n","protected":false},"author":1000,"featured_media":7115,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"wprm-recipe-roundup-name":"","wprm-recipe-roundup-description":"","site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[122],"tags":[],"class_list":["post-1250","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-understanding-metabolic-disorders"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\r\n<title>What is GMP? - Nutricia Metabolics North America \u2013 Products &amp; Support<\/title>\r\n<meta name=\"description\" content=\"GMP can be used as a protein source for phenylketonuria (PKU) &amp; tyrosinemia (TYR) formulas. 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