{"id":3578,"date":"2021-03-08T23:13:44","date_gmt":"2021-03-09T04:13:44","guid":{"rendered":"https:\/\/nutriciametabolics.expressodesign.com\/?page_id=3578"},"modified":"2025-05-15T12:24:55","modified_gmt":"2025-05-15T16:24:55","slug":"mma-pa","status":"publish","type":"page","link":"https:\/\/www.nutriciametabolics.com\/en-us\/mma-pa\/","title":{"rendered":"MMA\/PA &#8211; Methylmalonic &#038; Propionic Acidemia"},"content":{"rendered":"\n<h1>\n\t\tMMA\/PA &#8211; Methylmalonic &#038; Propionic Acidemia education &#038; Support\n\t<\/h1>\n\t<p><a href=\"#what-are-mma-pa\">What are MMA\/PA?<\/a>\u00a0 |\u00a0 <a href=\"#what-is-mma-pa\">MMA\/PA<\/a><a href=\"#education\">\u00a0Education<\/a>\u00a0 |\u00a0 <a href=\"#what-is-mma-pa\">MMA\/PA<\/a><a href=\"#resources\">\u00a0Resources<\/a>\u00a0 |\u00a0 <a href=\"#low-pro-living-support\">Low Pro Living Support<\/a>\u00a0 |\u00a0 <a href=\"#products\">Nutricia Products\u00a0<\/a><\/p>\n\t<iframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\/\/www.youtube.com\/embed\/caUpZ33HHTI?rel=0\" title=\"YouTube video player\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe>\n\t\t\t\t\t\t<h4>What are Methylmalonic Acidemia and Propionic Acidemia?<\/h4>\n\t\t\t<p>Methylmalonic acidemia (MMA) and propionic acidemia (PA) are inherited, genetic disorders. Both are caused by defects in enzymes that are needed to break down protein. Protein is made up of amino acids, which are important to build muscle and other body tissues for normal growth. Any extra amino acids are normally broken down to produce energy. In MMA and PA, four of the amino acids cannot be broken down but instead produce toxic acids in the body. These amino acids are <strong>methionine, isoleucine, threonine<\/strong> and <strong>valine<\/strong>, which are called &#8220;propiogenic amino acids.&#8221;<\/p>\n<p>When someone with MMA or PA either eats too much protein from food, does not get enough calories or becomes ill, blood levels of the propiogenic amino acids increase and so do their toxic byproducts. The toxic acids are methylmalonic acid, which is present in MMA, and propionic acid, which is present in both MMA and PA. Bacteria in the digestive system also produce propionic acid. Both toxic acids can cause serious and life-threatening health problems. The enzyme that is missing or not working properly in MMA it is called methylmalonyl-CoA mutase, and in PA it is called propionyl-CoA carboxylase.<\/p>\n<p>High blood levels of propiogenic amino acids and their related toxic acids can cause many health problems including poor feeding, vomiting, severe weakness (lethargy), seizures and coma. If not treated aggressively, both disorders can be life-threatening. Long term problems can include poor growth, abnormal movements (also called ataxia) and learning problems.<\/p>\n<p>Finding out that your child is diagnosed with MMA or PA can be overwhelming. Fortunately, nutrition management is available to help prevent many of these problems. Take comfort in knowing that your metabolic healthcare team can provide you with the best advice to help manage the disorder.<\/p>\n<p><strong>Incidence, Genetics and Newborn Screening<\/strong><\/p>\n<p>MMA and PA are rare disorders that occur in about 1 in every 80,000 to 100,000 births.<\/p>\n<p>Both MMA or PA are inherited as &#8220;recessive disorders.&#8221; In recessive disorders, both the mother and father are &#8220;carriers,&#8221; and they do not have any symptoms of the disorder. With each pregnancy there is a 1 in 4 (25%) chance that the infant will be affected. A genetic counselor can help explain the inheritance of the disorder and the risks to future infants.<\/p>\n<p>Both MMA and PA can be screened for at birth through a simple blood test. For details on newborn screening (NBS) in the US, visit\u00a0 <a href=\"https:\/\/newbornscreening.hrsa.gov\/your-state\" target=\"_blank\" rel=\"noopener\">https:\/\/newbornscreening.hrsa.gov\/your-state<\/a>; for information on NBS in Canada, visit <a href=\"https:\/\/www.raredisorders.ca\/\" target=\"_blank\" rel=\"noopener\">https:\/\/www.raredisorders.ca\/<\/a>.<\/p>\n\t\t\t\t\t\t<h4>Management of Methylmalonic and Propionic Acidemia<\/h4>\n\t\t\t<p>There is no cure for MMA or PA, but they can be managed with a modified diet, medication, and special medical formulas specifically designed for persons with MMA or PA. The modified diet for these disorders is low in propiogenic amino acids. It is important that an individual with MMA or PA continues with management as directed by their healthcare professional.<\/p>\n<p>A medical formula may be an important part of the diet for MMA and PA. The protein source in MMA and PA medical formulas is individual amino acids, but the four propiogenic amino acids are either not included or two of the four are included at small amounts. This allows a person with MMA or PA to get enough protein without the parts of the protein that can be harmful. Medical formulas may also provide calories, vitamins and minerals the body needs for normal growth.<\/p>\n<p>To provide just enough of the propiogenic amino acids that a person with MMA or PA needs, a limited amount of natural protein-containing foods are allowed in the diet. For infants, breast milk or regular infant formula is given in precise amounts. As the baby grows and can eat solid foods, the breast milk or regular infant formula will be removed from the diet, and the propiogenic amino acids will come from foods instead. Some individuals with MMA or PA may require a feeding tube. When a feeding tube is used all of the nutrients may come from MMA\/PA formula and either breast milk or regular formula.<\/p>\n<p>Since all foods with protein contain the four propiogenic amino acids, individuals with MMA or PA must limit their intake of foods high in protein. These include milk and dairy products, meat, poultry, fish, eggs, beans, nuts and peanut butter. Regular breads and pastas may be allowed in certain amounts, but special low protein versions of these foods are often used instead. Vegetables and fruits are allowed. Foods may be weighed or measured to ensure that excess protein is not eaten. Typically, the amount of protein in the diet is counted. A metabolic dietitian will work closely with people with MMA or PA to prescribe the best diet plan and help with needed changes in the future.<\/p>\n<p>Nutricia North America provides a range of medical formulas as well as low protein foods. Please contact us for more information. Your dietitian will help you decide which products are best.<\/p>\n<p>Some people with MMA have a form of the disorder that is called &#8220;vitamin B<sub>12<\/sub> responsive.&#8221; For these people, high doses of vitamin B<sub>12<\/sub> may be given as an injection to help reduce levels of methylmalonic acid in the blood.<\/p>\n<p>A drug called L-carnitine may be prescribed to those with MMA and PA. L-carnitine binds to propionic acid or methylmalonic acid and thus reduces the toxicity of these acids. Your metabolic doctor will decide if L-carnitine or other drugs are needed. For some patients, a liver transplant may be an option.<\/p>\n<p><strong>During Illness<\/strong><\/p>\n<p>During an illness or after an injury, the body increases the breakdown of protein stores. For those with MMA or PA, this can increase the level of propionic or methylmalonic acid in the blood. This can lead to serious medical problems. Early signs of illness include vomiting, excessive sleepiness, coordination problems and\/or changes in mental status. During any illness or after an injury, it is very important to notify a metabolic clinic immediately. Often, the diet is changed to decrease protein and increase calories. This can help slow down the breakdown of protein stores. Your clinic will give you an emergency letter &#8211; if you notice signs of high propionic or methylmalonic acid levels, take this letter to the emergency room. During serious illness, a hospital stay may be needed.<\/p>\n\t\t\t\t\t\t<h4>Resources and Family Support Groups<\/h4>\n\t\t\t<table width=\"660\">\n<tbody>\n<tr>\n<td width=\"660\"><a href=\"http:\/\/www.newbornscreening.info\/\" target=\"_blank\" rel=\"noopener\">Screening Technologies and Research in Genetics (STAR-G)<\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"660\"><a href=\"https:\/\/newbornscreening.hrsa.gov\/your-state\" target=\"_blank\" rel=\"noopener\">Newborn Screening in Your State (US)<\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"660\"><a href=\"https:\/\/www.oaanews.org\/\" target=\"_blank\" rel=\"noopener\">Organic Acidemia Association<\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"660\"><a href=\"https:\/\/www.pafoundation.com\/\" target=\"_blank\" rel=\"noopener\">Propionic Acidemia Foundation<\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"660\"><a href=\"https:\/\/www.raredisorders.ca\/\" target=\"_blank\" rel=\"noopener\">Canadian Organization for Rare Disorders<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><em>Nutricia North America would like to thank Sandy van Calcar, PhD, RD, Oregon Health &amp; Science University for her consultation.<\/em><\/p>\n\t\t\t<a href=\"\/en-us\/wp-content\/uploads\/2021\/05\/MMAPA-FactSheet.pdf\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t\tDownload MMA\/PA Fact Sheet\n\t\t\t<\/a>\n<h2>\n\t\tMMA\/PA Education\n\t<\/h2>\n<h3>\n\t\tTools Enabling Metabolic Parents Learning (TEMPLE)\n\t<\/h3>\n\t<p>This easy-to-understand education booklet and video are for families affected by a diagnosis of MMA\/PA. The book and video share the basics of the disorder and the genetics behind MMA\/PA.<\/p>\n<p>Click on the booklet to view and download in your preferred language.<\/p>\n\t<iframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\/\/www.youtube.com\/embed\/caUpZ33HHTI?rel=0\" title=\"YouTube video player\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe>\n<h2>\n\t\tMMA\/PA Resources\n\t<\/h2>\n\t\t\t\t<a href=\"\/en-us\/wp-content\/uploads\/2021\/02\/EarlyYearsCaregiverGuide22.pdf\" target=\"_blank\" rel=\"noopener\" itemprop=\"url\">\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.nutriciametabolics.com\/en-us\/wp-content\/uploads\/2021\/07\/EarlyYearsCaregiversGuide.jpg\" alt=\"Early Years Caregiver Guide book\" title=\"Early Years Caregiver Guide photo\" itemprop=\"image\"  \/>\n\t\t\t\t\t\t<\/a>\n\t<p><a href=\"\/en-us\/wp-content\/uploads\/2021\/02\/EarlyYearsCaregiverGuide22.pdf\" target=\"_blank\" rel=\"noopener\" aria-describedby=\"audioeye_new_window_message\">Caregiver&#8217;s Guide<\/a><\/p>\n\n<p><!-- Layout, Style or Voice Helpers --><\/p>\n<p><!-- Compliance --><\/p>\n<p><!-- For autoSmartRem addNewWindowWarnings div is referenced in an aria-describedby --><\/p>\nOpens in new window\nPDF Download\nWord Download\nExcel Download\nPowerPoint Download\nDocument Download\n\n<p><!-- Versioning Control Panel if versioning = true ! --> <!-- Launcher -->  <!-- Toolbar -->  <!-- Site Menu -->  <!-- Generic Aria Live message container --><\/p>\n<p><!-- Symbol definitions --><\/p>\n<p><!-- end #ae_app --><\/p>\n\n<p><!-- Layout, Style or Voice Helpers --><\/p>\n<p><!-- Compliance --><\/p>\n<p><!-- For autoSmartRem addNewWindowWarnings div is referenced in an aria-describedby --><\/p>\nOpens in new window\nPDF Download\nWord Download\nExcel Download\nPowerPoint Download\nDocument Download\n\n<p><!-- Versioning Control Panel if versioning = true ! --> <!-- Launcher -->  <!-- Toolbar -->  <!-- Site Menu -->  <!-- Generic Aria Live message container --><\/p>\n<p><!-- Symbol definitions --><\/p>\n<p><!-- end #ae_app --><\/p>\n\t\t\t\t<a href=\"\/en-us\/wp-content\/uploads\/2021\/04\/RMD-ActivityBook.pdf\" target=\"_blank\" rel=\"noopener\" itemprop=\"url\">\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.nutriciametabolics.com\/en-us\/wp-content\/uploads\/2021\/04\/RMD-ActivityBook.jpg\" alt=\"RMD Activity Book cover\" title=\"RMD Activity Book\" itemprop=\"image\"  \/>\n\t\t\t\t\t\t<\/a>\n\t<p><a href=\"\/en-us\/wp-content\/uploads\/2021\/04\/RMD-ActivityBook.pdf\" target=\"_blank\" rel=\"noopener\" aria-describedby=\"audioeye_new_window_message\">Activity Book (English)<\/a><\/p>\n\n<p><!-- Layout, Style or Voice Helpers --><\/p>\n<p><!-- Compliance --><\/p>\n<p><!-- For autoSmartRem addNewWindowWarnings div is referenced in an aria-describedby --><\/p>\nOpens in new window\nPDF Download\nWord Download\nExcel Download\nPowerPoint Download\nDocument Download\n\n<p><!-- Versioning Control Panel if versioning = true ! --> <!-- Launcher -->  <!-- Toolbar -->  <!-- Site Menu -->  <!-- Generic Aria Live message container --><\/p>\n<p><!-- Symbol definitions --><\/p>\n<p><!-- end #ae_app --><\/p>\n\n<p><!-- Layout, Style or Voice Helpers --><\/p>\n<p><!-- Compliance --><\/p>\n<p><!-- For autoSmartRem addNewWindowWarnings div is referenced in an aria-describedby --><\/p>\nOpens in new window\nPDF Download\nWord Download\nExcel Download\nPowerPoint Download\nDocument Download\n\n<p><!-- Versioning Control Panel if versioning = true ! --> <!-- Launcher -->  <!-- Toolbar -->  <!-- Site Menu -->  <!-- Generic Aria Live message container --><\/p>\n<p><!-- Symbol definitions --><\/p>\n<p><!-- end #ae_app --><\/p>\n\t\t\t\t<a href=\"\/en-us\/wp-content\/uploads\/2023\/10\/RMDActivityBook-SP.pdf\" target=\"_blank\" rel=\"noopener\" itemprop=\"url\">\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.nutriciametabolics.com\/en-us\/wp-content\/uploads\/2023\/10\/ActivityBookChildrenSPCover.jpg\" alt=\"ActivityBookChildrenSPCover\" title=\"ActivityBookChildrenSPCover\" itemprop=\"image\"  \/>\n\t\t\t\t\t\t<\/a>\n\t<p><a href=\"\/en-us\/wp-content\/uploads\/2023\/10\/RMDActivityBook-SP.pdf\" target=\"_blank\" rel=\"noopener\" aria-describedby=\"audioeye_new_window_message\">Activity Book (Spanish)<\/a><\/p>\n\n<p><!-- Layout, Style or Voice Helpers --><\/p>\n<p><!-- Compliance --><\/p>\n<p><!-- For autoSmartRem addNewWindowWarnings div is referenced in an aria-describedby --><\/p>\nOpens in new window\nPDF Download\nWord Download\nExcel Download\nPowerPoint Download\nDocument Download\n\n<p><!-- Versioning Control Panel if versioning = true ! --> <!-- Launcher -->  <!-- Toolbar -->  <!-- Site Menu -->  <!-- Generic Aria Live message container --><\/p>\n<p><!-- Symbol definitions --><\/p>\n<p><!-- end #ae_app --><\/p>\n\n<p><!-- Layout, Style or Voice Helpers --><\/p>\n<p><!-- Compliance --><\/p>\n<p><!-- For autoSmartRem addNewWindowWarnings div is referenced in an aria-describedby --><\/p>\nOpens in new window\nPDF Download\nWord Download\nExcel Download\nPowerPoint Download\nDocument Download\n\n<p><!-- Versioning Control Panel if versioning = true ! --> <!-- Launcher -->  <!-- Toolbar -->  <!-- Site Menu -->  <!-- Generic Aria Live message container --><\/p>\n<p><!-- Symbol definitions --><\/p>\n<p><!-- end #ae_app --><\/p>\n<h2>\n\t\tLow Pro Living Support\n\t<\/h2>\n\t<p>We have a library of information to help support families like yours throughout the various stages of life&#8217;s journey. From big moments, like starting college to little ones like what to eat for dinner, we have tips and ideas to help you along the way.<\/p>\n<h2>\n\t\tNutricia&#8217;s Family of MMA\/PA Metabolic Formula\n\t<\/h2>\n\t\t\t\t<a href=\"\/en-us\/shop\/category\/mma-pa-formulas\" target=\"_self\"  itemprop=\"url\">\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.nutriciametabolics.com\/en-us\/wp-content\/uploads\/2021\/04\/Product_Family_MMAPA.png\" alt=\"MMA\/PA formula packaging\" title=\"MMAPA Family\" itemprop=\"image\"  \/>\n\t\t\t\t\t\t<\/a>\n<h2>\n\t\tSupport For Your Whole Family\n\t<\/h2>\n\t\t\t\t<a href=\"\/en-us\/formula-coverage\/\" target=\"_self\"  itemprop=\"url\">\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.nutriciametabolics.com\/en-us\/wp-content\/uploads\/2021\/02\/nutriciametbolics-icon-coverage-support.png\" alt=\"Icon for Coverage Support\" title=\"Coverage Support Icon\" itemprop=\"image\"  \/>\n\t\t\t\t\t\t<\/a>\n\t<p>Coverage Support<\/p>\n\t\t\t\t<a href=\"\/en-us\/shop\/\" target=\"_self\"  itemprop=\"url\">\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.nutriciametabolics.com\/en-us\/wp-content\/uploads\/2021\/02\/nutriciametbolics-icon-products.png\" alt=\"Icon for Products\" title=\"Products icon\" itemprop=\"image\"  \/>\n\t\t\t\t\t\t<\/a>\n\t<p>Products<\/p>\n\t\t\t\t<a href=\"\/en-us\/low-protein-recipes\/\" target=\"_self\"  itemprop=\"url\">\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.nutriciametabolics.com\/en-us\/wp-content\/uploads\/2021\/02\/nutriciametbolics-icon-low-protein-recipes.png\" alt=\"Icon for Low Protein Recipe\" title=\"Low Protein Recipe Icon\" itemprop=\"image\"  \/>\n\t\t\t\t\t\t<\/a>\n\t<p>Low Protein Recipes<\/p>\n\t\t\t\t<a href=\"\/en-us\/blog\/\" target=\"_self\"  itemprop=\"url\">\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.nutriciametabolics.com\/en-us\/wp-content\/uploads\/2021\/02\/nutriciametbolics-icon-blog.png\" alt=\"Icon for Blog\" title=\"Blog icon\" itemprop=\"image\"  \/>\n\t\t\t\t\t\t<\/a>\n\t<p>Blog<\/p>\n\n","protected":false},"excerpt":{"rendered":"<p>MMA\/PA &#8211; Methylmalonic &#038; Propionic Acidemia education &#038; Support What are MMA\/PA?\u00a0 |\u00a0 MMA\/PA\u00a0Education\u00a0 |\u00a0 MMA\/PA\u00a0Resources\u00a0 |\u00a0 Low Pro Living Support\u00a0 |\u00a0 Nutricia Products\u00a0 What are Methylmalonic Acidemia and Propionic Acidemia? Methylmalonic acidemia (MMA) and propionic acidemia (PA) are inherited, genetic disorders. Both are caused by defects in enzymes that are needed to break down [&hellip;]<\/p>\n","protected":false},"author":1001,"featured_media":4446,"parent":0,"menu_order":6,"comment_status":"closed","ping_status":"closed","template":"","meta":{"wprm-recipe-roundup-name":"","wprm-recipe-roundup-description":"","site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-3578","page","type-page","status-publish","has-post-thumbnail","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\r\n<title>What is MMA\/PA? - Nutricia Metabolics North America \u2013 Products &amp; Support<\/title>\r\n<meta name=\"description\" content=\"What is MMA\/PA? Propionic acidemia (PA) and methylmalonic acidemia (MMA) are inherited, genetic disorders. Both are caused by defects in enzymes that are needed to break down protein.\" \/>\r\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\r\n<link rel=\"canonical\" href=\"https:\/\/www.nutriciametabolics.com\/en-us\/mma-pa\/\" \/>\r\n<meta property=\"og:locale\" content=\"en_US\" \/>\r\n<meta property=\"og:type\" content=\"article\" \/>\r\n<meta property=\"og:title\" content=\"What is MMA\/PA? - Nutricia Metabolics North America \u2013 Products &amp; Support\" \/>\r\n<meta property=\"og:description\" content=\"What is MMA\/PA? Propionic acidemia (PA) and methylmalonic acidemia (MMA) are inherited, genetic disorders. Both are caused by defects in enzymes that are needed to break down protein.\" \/>\r\n<meta property=\"og:url\" content=\"https:\/\/www.nutriciametabolics.com\/en-us\/mma-pa\/\" \/>\r\n<meta property=\"og:site_name\" content=\"Nutricia Metabolics North America \u2013 Products &amp; Support\" \/>\r\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/NutriciaMetabolicNutrition\" \/>\r\n<meta property=\"article:modified_time\" content=\"2025-05-15T16:24:55+00:00\" \/>\r\n<meta property=\"og:image\" content=\"https:\/\/www.nutriciametabolics.com\/en-us\/wp-content\/uploads\/2021\/04\/TEMPLE-MMA-PA-EN.jpg\" \/>\r\n\t<meta property=\"og:image:width\" content=\"600\" \/>\r\n\t<meta property=\"og:image:height\" content=\"451\" \/>\r\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\r\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\r\n<meta name=\"twitter:site\" content=\"@lowproliving\" \/>\r\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"7 minutes\" \/>\r\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/mma-pa\\\/\",\"url\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/mma-pa\\\/\",\"name\":\"What is MMA\\\/PA? - Nutricia Metabolics North America \u2013 Products &amp; Support\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/mma-pa\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/mma-pa\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/wp-content\\\/uploads\\\/2021\\\/04\\\/TEMPLE-MMA-PA-EN.jpg\",\"datePublished\":\"2021-03-09T04:13:44+00:00\",\"dateModified\":\"2025-05-15T16:24:55+00:00\",\"description\":\"What is MMA\\\/PA? Propionic acidemia (PA) and methylmalonic acidemia (MMA) are inherited, genetic disorders. Both are caused by defects in enzymes that are needed to break down protein.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/mma-pa\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/mma-pa\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/mma-pa\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/wp-content\\\/uploads\\\/2021\\\/04\\\/TEMPLE-MMA-PA-EN.jpg\",\"contentUrl\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/wp-content\\\/uploads\\\/2021\\\/04\\\/TEMPLE-MMA-PA-EN.jpg\",\"width\":600,\"height\":451,\"caption\":\"MMA\\\/PA (English)\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/mma-pa\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"MMA\\\/PA &#8211; Methylmalonic &#038; Propionic Acidemia\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/#website\",\"url\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/\",\"name\":\"Nutricia Metabolics North America \u2013 Products & Support\",\"description\":\"From little moments to big ones, we&#039;re here for you\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/#organization\",\"name\":\"Nutricia Metabolics North America \u2013 Products & Support\",\"url\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/wp-content\\\/uploads\\\/2020\\\/12\\\/nutricia-logo.png\",\"contentUrl\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/wp-content\\\/uploads\\\/2020\\\/12\\\/nutricia-logo.png\",\"width\":175,\"height\":60,\"caption\":\"Nutricia Metabolics North America \u2013 Products & Support\"},\"image\":{\"@id\":\"https:\\\/\\\/www.nutriciametabolics.com\\\/en-us\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/NutriciaMetabolicNutrition\",\"https:\\\/\\\/x.com\\\/lowproliving\",\"https:\\\/\\\/www.pinterest.com\\\/NutriciaMetabolics\\\/\",\"https:\\\/\\\/www.youtube.com\\\/user\\\/LowProLiving\",\"https:\\\/\\\/www.instagram.com\\\/nutriciametabolics\\\/\"]}]}<\/script>\r\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"What is MMA\/PA? - Nutricia Metabolics North America \u2013 Products &amp; Support","description":"What is MMA\/PA? Propionic acidemia (PA) and methylmalonic acidemia (MMA) are inherited, genetic disorders. Both are caused by defects in enzymes that are needed to break down protein.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.nutriciametabolics.com\/en-us\/mma-pa\/","og_locale":"en_US","og_type":"article","og_title":"What is MMA\/PA? - Nutricia Metabolics North America \u2013 Products &amp; Support","og_description":"What is MMA\/PA? Propionic acidemia (PA) and methylmalonic acidemia (MMA) are inherited, genetic disorders. Both are caused by defects in enzymes that are needed to break down protein.","og_url":"https:\/\/www.nutriciametabolics.com\/en-us\/mma-pa\/","og_site_name":"Nutricia Metabolics North America \u2013 Products &amp; Support","article_publisher":"https:\/\/www.facebook.com\/NutriciaMetabolicNutrition","article_modified_time":"2025-05-15T16:24:55+00:00","og_image":[{"width":600,"height":451,"url":"https:\/\/www.nutriciametabolics.com\/en-us\/wp-content\/uploads\/2021\/04\/TEMPLE-MMA-PA-EN.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_site":"@lowproliving","twitter_misc":{"Est. reading time":"7 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.nutriciametabolics.com\/en-us\/mma-pa\/","url":"https:\/\/www.nutriciametabolics.com\/en-us\/mma-pa\/","name":"What is MMA\/PA? - Nutricia Metabolics North America \u2013 Products &amp; Support","isPartOf":{"@id":"https:\/\/www.nutriciametabolics.com\/en-us\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.nutriciametabolics.com\/en-us\/mma-pa\/#primaryimage"},"image":{"@id":"https:\/\/www.nutriciametabolics.com\/en-us\/mma-pa\/#primaryimage"},"thumbnailUrl":"https:\/\/www.nutriciametabolics.com\/en-us\/wp-content\/uploads\/2021\/04\/TEMPLE-MMA-PA-EN.jpg","datePublished":"2021-03-09T04:13:44+00:00","dateModified":"2025-05-15T16:24:55+00:00","description":"What is MMA\/PA? Propionic acidemia (PA) and methylmalonic acidemia (MMA) are inherited, genetic disorders. Both are caused by defects in enzymes that are needed to break down protein.","breadcrumb":{"@id":"https:\/\/www.nutriciametabolics.com\/en-us\/mma-pa\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.nutriciametabolics.com\/en-us\/mma-pa\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.nutriciametabolics.com\/en-us\/mma-pa\/#primaryimage","url":"https:\/\/www.nutriciametabolics.com\/en-us\/wp-content\/uploads\/2021\/04\/TEMPLE-MMA-PA-EN.jpg","contentUrl":"https:\/\/www.nutriciametabolics.com\/en-us\/wp-content\/uploads\/2021\/04\/TEMPLE-MMA-PA-EN.jpg","width":600,"height":451,"caption":"MMA\/PA (English)"},{"@type":"BreadcrumbList","@id":"https:\/\/www.nutriciametabolics.com\/en-us\/mma-pa\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.nutriciametabolics.com\/en-us\/"},{"@type":"ListItem","position":2,"name":"MMA\/PA &#8211; Methylmalonic &#038; Propionic Acidemia"}]},{"@type":"WebSite","@id":"https:\/\/www.nutriciametabolics.com\/en-us\/#website","url":"https:\/\/www.nutriciametabolics.com\/en-us\/","name":"Nutricia Metabolics North America \u2013 Products & Support","description":"From little moments to big ones, we&#039;re here for you","publisher":{"@id":"https:\/\/www.nutriciametabolics.com\/en-us\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.nutriciametabolics.com\/en-us\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.nutriciametabolics.com\/en-us\/#organization","name":"Nutricia Metabolics North America \u2013 Products & Support","url":"https:\/\/www.nutriciametabolics.com\/en-us\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.nutriciametabolics.com\/en-us\/#\/schema\/logo\/image\/","url":"https:\/\/www.nutriciametabolics.com\/en-us\/wp-content\/uploads\/2020\/12\/nutricia-logo.png","contentUrl":"https:\/\/www.nutriciametabolics.com\/en-us\/wp-content\/uploads\/2020\/12\/nutricia-logo.png","width":175,"height":60,"caption":"Nutricia Metabolics North America \u2013 Products & Support"},"image":{"@id":"https:\/\/www.nutriciametabolics.com\/en-us\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/NutriciaMetabolicNutrition","https:\/\/x.com\/lowproliving","https:\/\/www.pinterest.com\/NutriciaMetabolics\/","https:\/\/www.youtube.com\/user\/LowProLiving","https:\/\/www.instagram.com\/nutriciametabolics\/"]}]}},"_links":{"self":[{"href":"https:\/\/www.nutriciametabolics.com\/en-us\/wp-json\/wp\/v2\/pages\/3578","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.nutriciametabolics.com\/en-us\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.nutriciametabolics.com\/en-us\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.nutriciametabolics.com\/en-us\/wp-json\/wp\/v2\/users\/1001"}],"replies":[{"embeddable":true,"href":"https:\/\/www.nutriciametabolics.com\/en-us\/wp-json\/wp\/v2\/comments?post=3578"}],"version-history":[{"count":11,"href":"https:\/\/www.nutriciametabolics.com\/en-us\/wp-json\/wp\/v2\/pages\/3578\/revisions"}],"predecessor-version":[{"id":9101,"href":"https:\/\/www.nutriciametabolics.com\/en-us\/wp-json\/wp\/v2\/pages\/3578\/revisions\/9101"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.nutriciametabolics.com\/en-us\/wp-json\/wp\/v2\/media\/4446"}],"wp:attachment":[{"href":"https:\/\/www.nutriciametabolics.com\/en-us\/wp-json\/wp\/v2\/media?parent=3578"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}